Upuść listę pandy indeksów

In [65]: df
Out[65]: 
       one  two
one      1    4
two      2    3
three    3    2
four     4    1


In [66]: df.drop(df.index[[1,3]])
Out[66]: 
       one  two
one      1    4
three    3    2
Smoggy Sandpiper